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Poster Sessions

 Arts and Humanities Division

MERLIE T. ANDERSON (Master’s Program) and Ivonna Smith, Department of Communication Sciences and Disorders, John H. Johnson School of Communications, Howard University, Washington, DC

GENDER CONSIDERATIONS IN THE DELIVERY OF CLINICAL SERVICES:  PART IV CLINICIAN-CLIENT INTERACTIONAL DISCOURSE

Gender differences are an integral component in clinician-client interactional discourse. Productive clinician-client discourse may provide useful information about a client’s functional use of language (Shipley, 2001). Male and female clinicians implement therapy differently.  Knowledge of theses differences will aid in the advancement of clinician-client relationships.  The research underlying this poster session examines male and female clinician differences in clinician-client interactional discourse.

Research Questions

  1. What are the main communication differences between males and females?
  2. What differences have been noted between male and female clinicians when eliciting interactional discourse?
  3. Does the client’s gender influence the male or female clinician’s behavior during interactional discourse?
  4. What modifications can be made during the interactional discourse to obtain the most accurate language sample?

 

KAWAII S. BALL (Master’s Program) and Joanna Losi, Department of Communication Sciences and Disorders, John H. Johnson School of Communications, Howard University, Washington, DC

GENDER CONSIDERATIONS AND THE DELIVERY OF CLINICAL SERVICES

Purpose:  As a result of the present research on gender behaviors, the learner will:

a.       Identify the role that gender plays between clinician stimulus (toy, manipulative selection, and activity choice) and client motivation, outcomes and goal progress.

b.      Distinguish between gender differences in the type of regulatory behaviors used in the clinical setting.

c.       Differentiate between gender reinforcement styles in language and material type and its positive or negative effects on client progress.

For years, researchers have raised questions concerning the affects that gender plays on the teaching styles of male and female teachers and speech clinicians.  Conventional philosophies of gender behaviors become unconventional as they raise significant concerns on how these differences affect communication therapy outcomes in children within the clinical setting. The level and type of clinician behavior introduced within the clinical setting has been studied to have possible effects on client progress outcomes. This study also tracks the differences in stimulus presentation as well as provides an analysis of the effects that varied types of reinforcement and regulation of student behavior from different gendered clinicians has on client outcomes and progress. Examination of “best practices” regarding clinician behavior when considering client gender is highlighted within the research study.

 

KOREN A. BEDEAU and Whitney B. Edwards (Doctoral Program), Department of Mass Communication and Media Studies and Caribbean Literature, John H. Johnson School of Communications, Howard University, Washington, DC

CARIBBEAN CARNIVAL:  Representation in Literature and Tourism Websites

Carnival is a major festival in Caribbean culture and is perhaps the most popular event to cross international borders. This indigenous cultural phenomenon has been recognized as a signifying practice for Caribbean writers and scholars in many disciplines, and continues to be a rich area for investigation. In literature, many scholars have theorized the Carnivalesque, which, broadly speaking, is the quality of a piece of fiction that incorporates aspects of Carnival both thematically and/or tropologically. Tourism studies have acknowledged the potential of Carnival as a cultural tourism product that attracts visitors and can contribute to economic development through the tourism industry.

Additionally, studies have critiqued the tourism industry for using stereotypical images when promoting and commodifying indigenous culture. The objective of the proposed interdisciplinary study is to analyze the differences of the depictions of Carnival and the utilization of the Carnivalesque aesthetic by examining the representation thereof in Caribbean literature and in tourism websites promoting travel to experience Carnival. We perceive this as an important project in order to contrast how Caribbean writers who, indeed, seem to validate and critically analyze the Carnival and its legacy, represent the Carnival with how the tourism industry, interested in attracting travelers with in a global market, tend to do so.

 

JEMEG V. DEES (Doctoral Program), Department of Counseling Psychology, School of Education, Howard University, Washington, DC 

NO LONGER A MYTH:  A STUDY OF THE HAPPY AND HEALTHY MARRIAGES OF AFRICAN AMERICAN MALE PROFESSIONAL ATHLETES

The marriages of professional athletes have been examined for years, but the positive factors in those marriages have rarely been observed. This study focuses on the factors that contribute to the strength and happiness in the marriages of professional athletes. This study addresses and identifies the unknown, or seldomly known, challenges which professional sports families encounter as well as how they overcome those challenges. The overall goal of this study was to learn how the healthy professional sports family copes and manages blending the world of high profile sports with home and family life.

The ABCX model was used as the theoretical framework to guide this study. The ABCX model was used to examine the stressors, the resources used to handle stressors, the definition of stressors, and the stress outcome that follows a crisis. This theory applies to the current study by examining how families of professional athletes cope with the stressors they face as a result of their husbands career.  The ABCX model provides structure in observing the ways in which these families cope.

Information was gathered from five couples in which the husband is currently a professional sports player, an inactive player, or a retired professional sports player. In order to meet eligibility requirements for this study a participant must:

1.      self-report that they have a strong marriage

2.      have been married for more than two years

3.      have been together in a committed relationship during husbands’ professional career if retired

4.      live within 3 hours of Washington, D.C. or be willing to participate in a phone interview

Participants in this study took part in open-ended, semi-structured couple interviews. The use of a qualitative design allowed a descriptive picture of the successful marriages of professional athletes to emerge. Using open-ended questions promoted discussion between partners and allowed them to share the factors and experiences they found the most relevant. In addition, a qualitative design allowed each couple to discuss in more detail the components that have contributed to their successful marriage.

Open communication, shared values, religion/ faith, and trust were consistently found to be important components contributing to the strength of these marriages. This study adds to the limited literature available discussing the positive aspects of professional athlete marriages.

 

PASCALE L. NELSON and Jacqueline S. Brown (Master’s Program), Department of Communication Sciences and Disorders, John H. Johnson School of Communications, Howard University, Washington, DC

GENDER PRESUPPOSITIONS IN CLINICAL TREATMENT IN SPEECH LANGUAGE PATHOLOGY

The current research suggests that there are differences between male and female clinicians and how they approach treatment. However, most clinicians are completely unaware of these variances and their effects. This study set out to determine whether or not clinicians have presuppositions about their clients derived from their own gender affiliation. Based on the review of the literature, it was determined that most clinicians do possess certain presuppositions based on the gender of the client and this also affects the course of treatment. These factors can have a major impact on how clinicians can intentionally or unintentionally affect their client outcomes. While some doubt the credibility of such findings, it is important to further analyze such data in search of more conclusive answers. Information such as this could prove to be extremely beneficial to current and future clinicians in their respective fields.

 

ANDREA L. TOLIVER-SMITH (Master's Program), Department of Communication Sciences and Disorders, John H. Johnson School of Communications, Howard University, Washington, DC

GENDER CONSIDERATIONS IN SERVICE DELIVERY;  PART III - RAPPORT

Literature involving gender differences in communication suggests that there are many differences between males and females and their communication styles which may have a direct impact upon the efficacy of therapy.  This study is a focus on non-verbal differences between male and female clinicians and the differences in communication styles across genders.   The areas that will be studied include paralanguage, proxemics and haptics, facial expressions and eye gaze.  The purpose of this study is to determine if there are gender differences in rapport during clinical interactions between the clinician and the client.

Learning outcomes:

  1. Clinicians will be able to identify their own gender communication style and make adjustments accordingly.

  2. Clinicians will be able to recognize client communication styles and tailor therapy activities across genders.

  3. Clinicians will become more effective in establishing and maintaining rapport with clients of either gender.

 

 

Biological and Life Sciences Division

 LOURETHA J. ADAMS (Doctoral Program), Department of Psychology, Graduate School, Howard University, Washington, DC

PERCEIVED STRESS AND QUALITY OF LIFE AMONG AFRICAN AMERICANS

Aside from poverty and inadequate medical care, there is one other condition that is especially burdensome too many African Americans no matter how much they earn or where they live:  psychological stress.  Many African Americans experience increased worries about violence, employment, or discrimination than other races. Endurance of such stressors keeps many African Americans in constant fight or flight state of  readiness, which overtime, may lead to the breakdown of normal physical vitality and may increase the body’s susceptibility to stress-related illnesses such as hypertension, cancer, heart disease, and stroke.  African Americans are more likely to suffer from these stress-related illnesses than whites. The residual effects of psychological stress also impacts Quality of Life (QOL) in areas such as diet, exercise, and sleep pattern. Studies have shown higher alcohol consumption and smoking in African Americans who report high stress levels. Research needs to examine the extent to which perceived stress might lead to decreased QOL. Objective: The purpose of this study was to assess the association between QOL and psychological stress. Methods: The present study population was comprised of 154 African Americans males and females, 18 years or older. Participants were administered the SF-36, which is a 36-item questionnaire that measures eight dimensions of health status: physical functioning, social functioning, role-physical, role emotional, mental health, vitality, bodily pain, and general health. Participants were also administered the Perceived Stress Scale (PSS), a measure that determines the degree to which individuals appraise situations in their lives as stressful. Results: Spearman rank-order correlations indicated that perceived stress scores negatively correlated with role physical (r = -.195, p < .05); role emotional (r = -.181, p < .05) health status dimensions. Perceived stress scores were also negatively correlated with the mental health summary measure (r = -.175, p < .05), but not with the physical health summary measure.   These findings show that psychological stress interferes with the optimal quality of physical and mental health.

This research investigation is part of a larger study entitled, "Stress and Psychoneuroimmunological Factors in Renal Health and Disease ," that is funded by The National Center on Minority Health and Health Disparities, Grant # 1P20 MD 000512-04

 

RACHEL E. AUSTIN (Master’s Program), Roxanne Christie, and Vernon Bond, Ed.D., Department of Health, Human Performance and Leisure Studies, Graduate School, Howard University, Washington, DC

AN EVALUATION OF THE DEGREE OF WHICH BODY COMPOSITION, CARDIOVASCULAR FITNESS, FAMILY HISTORY OF HYPERTENSION, AND THE ACE GENE I/D POLYMORPHISM INFLUENCE CARDIAC AUTONOMIC FUNCTION IN YOUNG ADULT AFRICAN-AMERICAN WOMEN

The autonomic nervous system plays an important role in developing hypertension, which is the leading health problem in the adult African American community. Heart rate variability (HRV) has emerged as a practical, noninvasive tool to quantitatively investigate cardiac autonomic modulation. Heart rate variability is influenced by many factors among which are identified in genetics, body composition, cardiovascular fitness, and parental history of hypertension.   The purpose of this study was to 1) examine the influence of genes, body composition, cardiovascular fitness, and familial history of hypertension on the cardiac autonomic modulation and 2) determine which risk factor provides the greatest contribution to the augmentation of HRV.  Twenty seven healthy African American women age 18 to 25 years participated in the study.  Each participant delivered saliva into an Oragene collection vial for the purpose of deoxyribonucleic acid (DNA) analysis.  The DNA isolated from saliva was genotyped for the ACE gene polymorphism.  Genotyping of the ACE polymorphism was determined using restriction enzyme digest.  Cardiovascular fitness (CF) was determined using a 6 minute sub-maximal exercise test to predict VO2peak.  Body composition was assessed using a duel-energy x-ray absorptiometry (DEXA) scan.  Information of family history of hypertension was obtained from a self-reported questionnaire.  While results showed a significant difference among the variant groups (high CF; 55.964 + 10.535 vs. low CF; 45.288 + 9.256 P=0.01, obese; 46.336 + 9.23, vs. non obese; 55.410 + 11.687 P=0.03, and familial history of hypertension; 44.422 + 9.603 vs. no familial history of hypertension; 54.521 + 10.302 P=0.015) in the high frequency (HF) HRV values, there was not a significant difference among the low CF vs. obese vs. familial history of hypertension groups.  In addition, there was no significant difference in HF HRV among individuals with the II (55.101 + 11.429) and the DD (49.399 + 10.021 P=0.411) ACE I/D polymorphism.  In conclusion, the findings of this study suggest that the genetic contribution of the ACE gene I/D polymorphism is important, but accounts for less of the variation observed in HRV than is due to cardiovascular fitness, body composition, and familial history of hypertension in young women. 

There was no financial research support for this study.

 

KEVIN O. BELGRAVE (Doctoral Program), Hassan Brim, Edward Lee, and Hassan Ashktorab, Department of Genetics and Human Genetics, Cancer Center  and G.I. Division, Department of Medicine, College of Medicine, Howard University, Washington, DC 

CHROMATIN MODIFICATION: H3 K9 EXPRESSION AND MICRO-SATELLITE INSTABILITY IN PATIENTS WITH COLON ADENOMA AND CANCER USING TISSUE MICROARRAY

The chromatin modification and activation of transcription and translation are important parts of gene regulation.  Recent studies have shown that gene activation is associated with chromatin loop formation and acetylation of histones.  It is not fully understood that how chromatin modification changes the progression of colon adenoma.  We proposed that he one major feature that determines the chromatin modification could be acetylation of H3 K9.  Thus, histone modification may modulate the degree and progression of colon cancer.  H3 K9 acetylation has been shown to be activated in solid tumors like prostate malignancies.  However, the role of H3 K9 acetylation in colon adenoma and carcinoma has not yet been determined.  This study was conducted to investigate the clinical value of acetylation of H3 K9 in colonic adenoma and carcinoma compared to normal tissue.  We used tissue slides from our patients undergoing elective G.I. colonoscopy at Howard University Hospital.  Expression of H3 K9 was determined by immunohistochemical staining of tissue microarrays from 41 and 4 cases of biopsy/resected colon adenoma and cancer specimens, respectively.  We evaluated H3 K9 expression and the correlation between expression of these proteins and various clinicopathological factors, including stage of the disease and microsatellite instability (MSI-H).  H3 K9 acethylation nuclear expression was observed in 90% and 10% of the cancer cases and adenoma, respectively compared to normal that was either negative of baseline positive.  All of the carcinomas were positive for MSI-H, while only all of the adenomas were positive for MSS.  H3 K9 expression was not correlated with MSI-H in the cancer lesion cases while the correlation may exist for the adenoma.  There was a no difference in clinicopathological parameters, such as tumor stage (T, N, and MSI-H was not found in those patients with Stage II and III disease.  These results suggest that H3 expression might be associated with proliferation, and tumor progression through up-regulation of oncogenes.  Further studies are needed to determine the role of H3 K9 in colon adenoma and cancer.

 

PAMELA A. G. CLARKE and William R. Eckberg, Ph.D., (Master’s Program) Department of Biology, Graduate School, Howard University, Washington, DC

THE EXPRESSION AND LOCALIZATION OF MELANOMA INHIBITORY ACTIVITY (MIA) AND ITS FUNCTIONAL ROLE IN BREAST CANCER

Melanoma Inhibitory Activity (MIA) is a small, secreted protein normally expressed in chondrocytes and appears to be a pivotal player in their differentiation. Initially identified as a tumor suppressor, MIA is now a major metastatic marker for melanoma and has been identified as a key molecule in melanoma tumor progression. Melanoma patients expressing high levels of serum MIA have a poor prognosis and exhibit a reduced response to various chemotherapeutic agents. This observation prompted us to look for a correlation between MIA levels and metastatic potential in breast cancer cell lines. The cell lines chosen ranged from minimally to highly metastatic. We examined the expression and localization of MIA by western blot, RT-PCR and immunofluorescence. Western blot and RT-PCR detected MIA in the MDA-MB 435, MDA-MB 231, MCF-7, SKBR3, T-47 D and SKMEL5 (melanoma control) cell lines.  RT-PCR and western blot analysis revealed relatively high MIA mRNA and protein levels respectively in MDA MB 435 and MDA MB 231, the two most metastatic cell lines. MIA was detected as diffuse staining throughout the cytoplasm of the breast cancer cells. Since a correlation between increased serum levels of malignant melanoma and more advanced metastatic disease has been established, we also investigated the amount of MIA secreted into the supernatant by ELISA (Enzyme-Linked Immuno Sorbent Assay) and western blot analysis. MIA secreted protein levels were significantly higher in the MDA MB 435 and MDA MB 231 cell lines in comparison to the other cells lines tested. Analyses of preliminary data suggest a positive correlation between MIA expression and tumor progression in these cell lines as in melanoma and some other cancer cells. Hence, MIA has the potential of being a predictive marker for patients’ outcomes in breast cancer.

Supported by: NSF HRD-0401697

 

SUSSAN E. EKEJIUBA1 (Doctoral Program), Martha I. Dávila-García1, Elizabeth Adetobi-Oladele1, Machiko Shirahata2, Anthony Caparso3, V. John Massari1. Department of Pharmacology, College of Medicine, Howard University, Washington, DC, 2Johns Hopkins University, Baltimore, MD, 3Boston Scientific, Natick, MA   

Differential Distribution of Cardiac Afferents into Nucleus Tractus Solitarius from Intraventricular Septal Ganglion and their colocalization with Substance P

Responses of the heart to vagal stimulation are relayed back to the CNS via afferents to the nucleus tractus solitarius (NTS).  This circuitry selectively regulates heart dromotropic, inotropic and chronotropic functions.  A large parasympathetic intracardiac ganglion, the intraventricular septal ganglion (IVSg) projects to both left and right ventricles and seems to be involved with cardiac contractility.  In the present study we wanted to determine if sensory pathways would play a role in the CNS-cardiac circuitry of the IVSg.  Afferent projections from the heart were retrogradely labelled by injections of CTB-HRP into the IVSg.  A left intercostal thoracotomy was performed in 9 male cats weighing 2.5-6.5 kg. A solution of 1% CTB-HRP was injected (25 µl) into the IVSg in 5 animals or into the pericardial sac (PCS) in 4 animals. Injections were also performed into the ventral side of the tongue (3 µl) in all cats to determine retrograde label viability.  The CTB-HRP labeled terminals were exclusively confined to the dorsolateral, dorsomedial and commissural NTS at the level of the area postrema in all 5 cats receiving IVSg injections and were colocalized with positive immunolabel for substance P. The labeled terminals were present on both right and left NTS but were more abundant on the left NTS.  Hypoglossal neurons were positively labelled for CTH-HRP on all cats. No labeled terminals were observed when a 1% CTB-HRP solution was injected into the PCS. The transganglionic transport to the NTS appears to be through the vagus nerve as vagal fibers were also CTB-HRP positive. This suggests that there are sensory afferents to IVSg in cats, probably from the nodose ganglion, which project to the dorsomedial, dorsolateral and commissural NTS. Since previous work from this laboratory has established the presence of projections from NTS neurons to the nucleus ambiguus (NA), this suggests that the control of NA neurons projecting to IVSg may be selectively modulated by left dorsomedial, dorsolateral and/or commissural NTS neurons.

 

This research was supported by NIH-NIGMCS 2S06GM008016 to MDG, NIH-NINDS-SNRP 2 U54 NS039407 to MDG and VJM, NIH-NIMH 1 R24MH067627 to MDG and VJM, NIH-RCMI 2 G12 RR003048 to MDG and Boston Scientific, Natick, MA to VJM.

 

Kenny M. Fournillier1 (Master’s Program), Wade C. Sherbrooke2, and Dr. George Middendorf1, 1Department of Biology, Graduate, School, Howard University, Washington, DC and 2American Museum of Natural History Southwestern Research Station

BLOOD SQUIRTING AS AN EFFECTIVE ANTI-PREDATORY MECHANISM IN PHRYNOSOMA (HORNED LIZARDS): A TEST USING MUSEUM SPECIMENS

The effectiveness of blood squirting as an anti-predatory mechanism was studied in Phrynosoma (Horned Lizards).  Body size and the prevalence of injuries were compared between blood squirting and non-blood squirting specimens using the Phrynosoma collection at the National Museum of Natural History (Smithsonian Institution).  Of the 924 specimens examined, blood squirting species showed a significantly larger body size than non-blood squirting species, suggesting that the ability to squirt blood may be determined by body size.  Using the premise that an injury is a sign of a failed predation event, a significantly greater number of blood squirting Phrynosoma showed injuries than non-blood squirting Phrynosoma, supporting the hypothesis that blood squirting is an effective anti-predatory mechanism that is based on body size.

 

BRUK GETACHEW (Doctoral Program), Sheketha R. Hauser, Robert Taylor, MD and Yousef Tizabi Department of Pharmacology, College of Medicine, Howard University, Washington, DC

Antidepressants Block Depressive-Like Behavior Following Alcohol Withdrawal In Rats: Implication For Relapse

Particularly high complaint of depression during alcohol withdrawal (AW) is thought to increase alcohol relapse risk. Previously, we have shown that withdrawal from 7 and 14 days of alcohol exposure results in depressive-like behavior in Wistar rats and exacerbates the existing depressive-like characteristics in Wistar-Kyoto (WKY) rats. In this study we sought to determine whether daily treatment with antidepressants during alcohol exposure can block the manifestation of depressive-like behavior following AW. Adult female WKY and their progenitor control, Wistar rats, were exposed for 3 hrs daily for 10 days ethanol via inhalation chambers followed by i.p injections of 10 mg/kg imipramine or nomifensine, selective norepinephrine and dopamine reuptake blockers, respectively. Mean blood alcohol levels (BALs) were maintained at approximately 150 mg/dL in both strains. On day 11 the animals were tested in a locomotor activity (LCA) monitoring cage for 10 min followed by assessment of their performance in Porsolt forced swim test (FST) for 5min. Neither imipramine nor nomifensine had any effect on LCA in Wistar rats. Imipramine reduced LCA in WKY rats only. Both imipramine and nomifensine blocked the exaggerated immobility in FST, reflective of the depressive characteristic, in both strains following AW. These data suggest that pretreatment with antidepressants may enhance treatment outcome for alcoholics by preventing depressive-like behavior following alcohol withdrawal.

Supported by: NIAAA P20 (AA014643) and NIH/NIMH (2SO6 GM08016-36) 

 

CRYSTAL M. GLOVER and Lloyd R. Sloan, Ph.D. (Doctoral Program), Department of Psychology, Graduate School, Howard University, Washington, DC

INTERACTIONS BETWEEN ETHNICITY, GENDER, AND INCOME INFLUENCE EVALUATIONS OF GROUPS

Categorization is at the core of many enduring and salient concepts that shape social psychology and society.  Traditionally, ethnicity and gender are two of the most salient categories that individuals base evaluations of the self and others upon. However, recognition mounts for socioeconomic status (SES) as a category individuals frequently use to evaluate and perceive others and themselves. With each categorization (i.e. ethnicity, gender, and SES) shaping evaluations and perceptions, beginning to understand how the simultaneous use of categories uniquely shapes an individual’s evaluations and perceptions is fascinating.

Investigating differential evaluations associated with multiple category groups based on variations in ethnic (African or White American), gender (men or women), and/or income (low-, middle-, or high-income) categorizations is the research goal.  Groups simultaneously representing an ethnic, gender, and income categorization are multiple category groups.

One hundred twenty participants provided evaluations of twelve multiple category groups: low-income African American men, low-income African American women, low-income White American men, low-income White American women, middle-income African American men, middle-income African American women, middle-income White American men, middle-income White American women, high-income African American men, high-income African American women, high-income White American men, and high-income White American women. Participants evaluated groups using Single Item Ratings (SIR). SIR measured the amount of favorability/unfavorability participants associated with each group. Assessment of the favorability of each group was along a 9-point Likert-type scale with endpoints 1(very unfavorably) and 9 (very favorably).

This research employed  a 2 (target ethnicity: African-and White-American) X 2 (target gender: men and women) X 3 (target income: low-, middle-, and high-income) between subjects design. The General Linear Model (GLM) – Univariate tested significant main effects of and interactions between ethnicity, gender, and income on overall evaluations of each group.  Results indicated a 3-way interaction between ethnicity, gender, and income (F = 3.03, p=.05).  This result suggests that ethnicity, gender, and income interact with one another to shape others’ global evaluations of various groups. In addition, results indicated main effects for ethnicity (F=25.03, p=.00), gender (F=4.16, p=.04), and income (F=40.69, p=.00). Main effects suggest that each categorization influences participants’ evaluations of groups.

As a whole, results indicate composite effects of ethnicity, gender, and income are not simply additive, but interactive. Evaluations of multiple category groups are distinct from the evaluations of groups based solely on ethnicity, gender, or income. However, ethnicity, gender, and income are (important) independent factors in evaluations of multiple category groups.

 

LARRY D. KEEN II and Arlener D. Turner, (Master’s Program), Clive Callender, M.D., Ernest Carter, M.D., Jules Harrell, Ph.D. and Alfonso Campbell, Ph.D., Department of Psychology and College of Medicine, Howard University, Washington, DC

INDICES OF LIPID METABOLISM AND BLOOD PRESSURE AS PRDICTORS OF CVLT PERFORMANCE IN A COMMUNITY-BASED COHORT OF AFRICAN AMERICANS

Objective:  Recent studies show that vascular disease risk factors, more specifically elevated serum Triglyceride levels, high serum Total Cholesterol (TC) and High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL) are important in the development of memory impairments in elderly populations.  Elderly African American populations with a high prevalence of vascular disease may be at particular risk for neurocognitive impairment.  The purpose of the current study was to examine in a middle-aged (mean age = 46.15 years) African American sample the relationship between vascular disease risk factors and verbal memory task performances.  As dementia is less frequent among middle aged adults, it seems important to determine whether these risk factors are related to memory functions in a younger population. 

Methods:  The California Verbal Learning Test (CVLT), a measure of episodic memory functions, was administered to 187 (male = 87, female = 100), African American participants aged 18 years or older and residing in the Washington, DC metropolitan area.  These participants were enrolled in a larger study that explores psychoneuroimmunological (PNI) factors and renal health.  At study entry, participants provided a urine and blood sample, and they were administered a battery of neuropsychological, psychosocial, and mood measures.  Blood pressure was also evaluated.  This study was conducted in the General Clinical Research Center (GCRC) at Howard University Hospital.

Results/Conclusion:  Preliminary findings show that serum triglyceride levels correlated with trials 1-5 along with total recall (Trial 1: r = -.219 R2=.048 p =.039, Trial 2: r =.212 R2 = .045 p= .046, Trial 3: r =-.239 R2 = .057 p =.024, Trial 4: r = -.211 R2 = .044 p = .047, Trial 5: -.253 R2 = .064 p = .017, Total Recall: r = -.266R2 = .071 p = .012).  Among the vascular risk factors triglycerides were also the strongest predictor of CVLT performance.  Diastolic blood pressures also served as significant predictors.  These findings are consistent with the view that lipid abnormalities and elevated diastolic blood pressure may contribute to conditions that compromise the integrity of arterial vessel walls and impede the blood flow to brain regions that support memory functions.

This research investigation is part of a larger study entitled, “Stress and Psychoneuroimmunological Factors in Renal Health and Disease,” that is funded by The National Center on Minority Health and Health Disparities, Grant # 1P20 MD 000512-04.

 

April Moon-Hodges(Doctoral Program), Allan Johnson, and Barbara Harland.  Department of Nutritional Sciences, Graduate School, Howard University, Washington, DC

INFLUENCES OF DIETARY CARBOHYDRATES AND LIPIDS ON THE PARAMETERS OF THE METABOLIC SYNDROME

Metabolic syndrome describes the presence of a cluster of metabolic abnormalities associated with type 2 diabetes mellitus and cardiovascular risk.  Diet may play a role in the modification of this syndrome.  The objective of this study was to investigate the dietary carbohydrates and lipids on the parameters of metabolic syndrome.  Secondary analysis of data from the 1999-2000 National Health and Nutrition Examination Survey was conducted.  Subjects were matched by energy intake and assigned to one of three groups (49 in each group):  The High Fat/Low Carbohydrate group (HF/LC) the Low Fat/High Carbohydrate group (LF/HC), or the Low Fat/Low Carbohydrate group (LF/LC). High fat was>30% calories from fat, low fat was<30% calories from fat, high carbohydrate was>60% calories from carbohydrate, and low carbohydrate was <60% calories from carbohydrate.  Data were analyzed using SUDAAN (RTI International, Research Triangle Park, Raleigh, NC).  Parameters of the three groups were compared using Student’s t-tests (p<0.05).  The HF/LC group had a significantly higher mean waist circumference than the LF/LC group (Mean ± SEM, 92.0 ± 2.6 cm vs. 84.7 ± 2.2 cm). The LF/HC group had a significantly lower High Density Lipoprotein Cholesterol concentration than the HF/LC group (49.3 ± 1.9 mg/dL vs. 55.3 ± 2.2 mg/dL). The LF/LC group had a significantly higher mean blood glucose level than the HF/LC group (84.8 ± 1.2 mg/dL vs. 81.1 ±1.0 mg/dL). The LF/LC group also had a significantly higher mean blood glucose level than the LF/HC group (84.8 ± 1.2 mg/dL vs. ± 81.1 ± 1.0 mg/dL).  None of the groups met the criteria needed to be classified as having metabolic syndrome.

 

DEBRA L. MOREHEAD (Master’s Program), Department of Psychology, Graduate School, Howard University, Washington, DC

C-REACTIVE PROTEIN AND BODY MASS INDEX IN A COMMUNITY-BASED STUDY OF AFRICAN AMERICANS

Obesity/overweight has reached epidemic proportions in the United States.  Obesity/overweight, in addition to type 2 diabetes and hypertension, are leading risk factors for cardiovascular disease. These diseases account for 20 percent of deaths among blacks in the U.S., twice the figure for whites (Cooper et al, 1999).  Studies utilizing African-American men (Douglas et al, 2004) and women (Miller et al, 2003; Ford, 1999) show that overweight/obesity, as indexed by unhealthy fat accumulation,  is positively associated with C-reactive protein (CRP) levels.  Serum CRP is an acute-phase protein produced by the liver in response to inflammation, infection, tissue damage, and trauma.  CRP is primarily regulated by the proinflammatory cytokine interleukin-6 (IL-6).  Body fat is typically measured by the body mass index (BMI).  BMI values in the range of 25-29 kg/m² serve as the standard for overweight.  Higher BMI values above 30 kg/m² denote the standard for obesity.  Objective:  To investigate the relationship between CRP and BMI in a community-based study of African Americans.  Hypothesis:  African Americans who have higher concentrations of CRP, will have higher BMIs.  Methods:  Seventy-eight (N=78) African Americans (males and females), 18 years of age and older, were the participants in this study and were treated as genetically unrelated.  ELISA assay procedures were used to determine serum CRP levels; and, weight and height measurements were used to calculate BMI.  Results:  As predicted, higher CRP levels were associated with higher BMI values (r =.608, p ≤ 0.01) (2-tailed).  Conclusion:  These findings provide support for the idea that obesity/overweight is an inflammatory related disease.  Implication:  There is a need to identify the underlying biopsychosocial mechanisms that contribute to the problem of overweight/obesity.  

The research investigation is part of a larger study entitled, “Stress and Psychoneuroimmunological Factors in Renal Health and Disease,” that is funded by The National Center on Minority Health and Health Disparities, Grant #1P20MD000512-04.

 

JEANNINE S. SKINNER (Master’s Program), Alphonso Campbell, Ph.D., Jules P. Harrell, Ph.D., Department of Psychology, Clive Callender, Graduate School and College of Medicine, Howard University, Washington, DC

THE RELATIONSHIP BETWEEN DEPRESSION, ANXIETY, RELIGIOSITY AND BLOOD PRESSURE IN A COMMUNITY- BASED SAMPLE OF AFRICAN AMERICANS

 Objective: Past research has consistently shown that depressive symptomatology and symptoms of anxiety are adversely related to physical health outcomes. Research has also shown that positive coping mechanisms can help mitigate feelings of depression and anxiety and ultimately lead to an improvement in health- related quality of life. Using a sample of African- Americans, the purpose of this study was to examine the relationship between depressive affect anxiety, religiosity, and blood pressure. More specifically, this study sought to determine whether anxiety and depression served as predictors of blood pressure in African- Americans. A second aim of this study was to assess whether the relationship between depressive affect, anxiety, and blood pressure was moderated by religiosity.

 Method:  Participants included a community-based sample of 172 African-Americans (84 males, 88 females), 18 years of age or older.

 Results:  Study findings indicated significant correlations between depressive affect and diastolic blood pressure (r=.169, p= .029), depressive affect and anxiety (r=.426, p=.01), and religious participation and anxiety (r=-.209, p=.020).  Regression analysis revealed depressive affect to be a significant predictor of diastolic blood pressure (R²= .029, R²adj= .023, p<.05, beta= .169).

Conclusion: Although, anxiety and religious participation were not significant predictors of blood pressure, results from this study showed depressive affect to be a significant predictor of diastolic blood pressure in African- Americans. These findings suggest that depressive affect may be instrumental in   health- related quality of life. Research limitations and future directions will be discussed. 

This research investigation is part of a larger study entitled, "Stress and Psychoneuroimmunological Factors in Renal Health and Disease ," that is funded by The National Center on Minority Health and Health Disparities, Grant # 1P20 MD 000512-04

 

TAMARA D. WILLIS (Doctoral Program), Department of Psychology and Center for Urban Progress, Graduate School, Howard University, Washington, DC

PUBLIC HOUSING, SAFETY, AND HEALTH STATUS

BACKGROUND:  Prior studies have demonstrated associations among environment, neighborhood, and socioeconomic status, suggesting that these factors contribute to overall health.  Public housing residents may experience disproportionate levels of physical and mental health due to compromised neighborhood safety.

OBJECTIVE:  The current research investigated perceptions of household physical health and psychological well-being, access to health care, and neighborhood safety in a sample of public housing residents.  METHOD:  An interview survey was developed by study collaborators to ascertain respondents’ demographic information and perceptions of their experiences as public housing residents.  Focus groups were also conducted to gain additional insight into residents’ perspectives.  After informed consent was obtained, a team of research assistants administered the interview survey to 190 individuals identified as heads of household residing in a Washington, DC public housing development.  Upon completion of the interview survey, participants were given a nominal remuneration for their time.  Data pertaining to respondents’ self-reported household composition, sources of income, educational background, medical and mental health conditions, access to health care services, and perceptions of public safety were analyzed using SPSS.  RESULTS:  Frequency analyses showed that high blood pressure was the leading physical health ailment among nearly the majority of respondents, while depression was the psychological ailment most often reported by nearly one-third of respondents, followed closely by anxiety.  Further, the vast majority of respondents reported having access to health care, chiefly in the form of Health Maintenance Organization membership, and health insurance, most often Medicaid. Respondents’ concerns about public safety were clearly reflected in response rates for these items.  Particularly, most residents reported not feeling safe in their neighborhood because of the persistent presence of drug-related activities in specific areas of the housing development. 

CONCLUSION:  These findings provide evidence that health status may be associated with neighborhood safety status.  Interventions that foster community empowerment and aim at eliminating threats to public safety within public housing communities should be identified and implemented in an effort to reduce the burden of medical illness and psychological distress experienced by public housing residents. 

This study was conducted by the Howard University Center for Urban Progress in collaboration with the Lincoln Heights New Community Partnership, the District of Columbia Government, and the DC Housing Authority with funding from the DC Housing Enterprise.

 

XUNQIN YIN (Doctoral Program) and WILLIAM R. ECKBERG, Ph.D., Department of Biology, Graduate School, Howard University, Washington, DC

 IDENTIFICATION OF PHOSPHOLIPASES C (PLC) AND THEIR POSSIBLE ROLES IN CHAETOPTERUS EGG ACTIVATION

Phospholipase C is a central enzyme involved in the calcium release of egg activation by the proposed G-protein-PLCb and/or protein tyrosine kinase (PTK)-PLCg signal pathways. In present study, we for the first time cloned cDNAs encoding PLCβ and PLCγ isoforms from Chaetopterus eggs by RT/DOP-PCR and rapid amplification of cDNA end PCR (RACE PCR). By western blot analysis, PLCβ (135kDa) and PLCγ (150kDa) were expressed in the eggs. Treatment of eggs with general PLC inhibitor, U-73122, egg activation was inhibited.  We further tested the egg activation was G protein-PLCβ and/or PTK-PLCγ dependent. The agonist and antagonist of G protein, chorela toxin (CTX) and pertussis toxin (PTX) both had no significant effects in egg activation. However, the antagonists of PTK, genistein and typhostein B42, both blocked the egg activation in a dose-dependent manner. Our data suggests that the PLC activity from the egg is required for the egg activation and PLCg may play an important role through PTK-PLCg signal cascade during Chaetopterus egg activation.

 This research was supported by NSF HRD-0401697.

  

Engineering and Physical Sciences Division

YAO KOUWONOU (Master’s Program), Kimberly L. Jones, and Ramamoorthy Malaisamy Department of Civil Engineering, College of Engineering, Architecture and Computer Sciences, Howard University, Washington, DC

Biofouling Potential of Graft-surface Modified Micro-porous Polyethersulfone Membranes

Bio-fouling of membranes in water treatment process is considered a serious issue, as the presence of few counts of microorganism cells can grow rapidly and cause serious performance disorders. Since it is almost impossible to completely remove the microorganism during the treatment process, the tailoring the membrane properties in order to prevent bio-fouling gains more attention and importance. In this aspect, we are investigating on the incorporation of polymers having anti-fouling potential by graft-co-polymerization on the surface of the commercial polyethersulfone microfiltration membranes. In this case, a weak acid monomer, acrylic acid (AA) and a quaternary salt of acrylic polymer [2-(Acryloyloxy)ethyl]trimethylammonium chloride (AETMAC) are taken and the polymerization on the membrane surface is done using UV initiation at 254 nm. We confirmed the graft-modification of PES membranes with acrylic acid by determining the degree of grafting, ATR FT-IR spectroscopic analyses and streaming potential measurements. FT-IR spectra of the modified membranes show a peak corresponding to the –C=O group of the acid at around 1650 cm-1. The streaming potential measurements show an enhanced negative surface charge from -40mV to -80mV at a pH of 6.4, for a 0.1 µm PES membrane modified with 1mM acrylic acid. Interestingly, the pure water flux of modified 0.1 µm PES membranes at 20 psi, did not change appreciably, where as that of 0.22 µm increased from 2.5 L/(m2.S) to 3 L/(m2.S) after the modification. We are investigating on the solution flux and fouling of Escherichia Coli through the unmodified and modified membranes to compare their performance. In addition, we are striving to optimize the flux and the anti-biofouling potential of the modified membranes at dilute E.Coli concentrations. Optimization of flux and biofouling potential with various conditions and compositions and the studies on AETMAC modification are in progress.

 

JAMESE D. SIMS (Doctoral Program), Gregory Jenkins, Ph.D., Department of Atmospheric Sciences, College of Engineering, Architecture and Computer Sciences, Howard University, Washington, DC

 WRF-NMM MODEL VERIFICATION STUDIES FOR THE AMMA PROJECT DURING THE 2006 ATLANTIC HURRICANE

Over the past decade, the use of forecasting models has improved quite drastically.  This increase in accuracy is widely due to the greater access of data via satellites, upper air observations, and better representation of various processes in the predictive models.  This is particular in studying tropical cyclogenesis and hurricane evolution.  However, in the process of forecasting, it is important to know the accuracy of the tool that is used for atmospheric predictions.  During the summer of 2006, a field intensive observation program, the African Monsoon Multidisciplinary Analysis (AMMA) was conducted in West Africa.  In conjunction with AMMA, the National Center of Environmental Prediction (NCEP), and the NOAA Educational Partnership Program (NOAA/EPP), global and mesoscale model real-time forecasts were undertaken.  The focus of this presentation is on the verification of the WRF-NMM (Weather Research Forecast – Nonhydrostatic Mesoscale Model) version 2 run twice daily at 00Z and 12Z for 48 hour forecast from June 1 - October 1, 2006.  There are two domains in the WRF-NMM model covering the continental West Coast of Africa and the Eastern Tropical Atlantic Ocean; the outer parent domain is run at a 12km resolution and a one-way nested inner domain is run at 4km resolution.  The verification is done on the following parameters: 10m wind field, 850mb geopotential height, and precipitation.  These parameters are verified using the NCEP Forecast Verification Software and the NCEP QPF analysis.  Information collected from the verification process will evaluate the models’ performance on atmospheric conditions of West Africa occurring during June through September 2006.

 

Social Sciences Division

Ebony R. Custis (Master’s Program), Department of Sociology and Anthropology, Graduate School,  Howard University, Washington, DC

CULTURAL CAPITAL, CRITICAL THEORY, AND MOTIVATION FOR PARTICIPATION IN CAPOEIRA ANGOLA

This study addresses individual motivation for participation in the marginalized art form of Capoeira Angola (CA). CA is an internationally practiced Afro-Brazilian art form that includes song, instrument play, dance, spirituality, and play fighting.  This study will explore whether CA students are motivated by a desire for symbolic achievement, as suggested by critical theory.  Significantly, this study will explore whether critical theory or Bourdieu’s theory of cultural capital can best explain motivation for participation in CA.

Previous studies of marginalized art forms focus on the expression of the art form itself and frequently overlook the individual’s motivation to participate in the art form.  In detailing the observable dimensions of marginalized art forms, existing research has failed to specifically address how participants create and define their perception of the art form, and to identify the factors that define their choice to participate in the art form.

By using five qualitative procedures (participant observation, field notes, free lists, pile sorts, and semi-structured interviews), this study seeks to gain insight into individual’s conception of CA and how it informs CA students’ motivation for participation.  The combination of five distinct research methodologies constitutes an innovation in sociological research in that the added level of data analysis widens the use of theory and practice in sociological studies that examine cultural and artistic practices.

The overall significance of this study lies in its contribution to an increased intellectual and political awareness concerning marginalized cultural and artistic practices.  This study is relevant to contemporary social life in that it may increase our understanding of the role that these artistic practices potentially play in the genesis and persistence of social movements.

 

Valerie R. Stackman (Master’s Program), Department of Sociology and Anthropology, Graduate School, Howard University, Washington, DC

Stranger Danger: The Effects of COntact as Moderated by perceptions of Dangerousness on Attitudes towards persons with mental disorders

Negative attitudes in service industries can create barriers to effective care.  The purpose of this study is to contribute to the literature by determining the extent to which contact is altered by respondent’s perceptions of dangerousness in explaining attitudes towards persons with mental disorders as measured by desired social distance.  

This study will analyze data previously collected in the National Opinion Research Center’s 1996 General Social Survey module on Mental Health (N=1,170).  Two equations will be calculated to determine if perceived dangerousness moderates the effect of contact on attitudes: the logistic regression of attitudes (1) on contact; and (2) on contact and respondent’s perceptions of dangerousness of persons with mental disorders.  Analysis will determine statistical and substantive correlations in the equations.    Findings will be discussed with regard to the field of mental health and other service-oriented industries. 

Source of Financial Research Support:  None.

 

UNDERGRADUATE

Poster Sessions

 

Arts and Humanities Division

Ashley N. Pugh, Department of Human Development and Psycho-educational Studies, School of Education, S. R. Hauser1, Department of Psychology, College of Arts and Sciences, B. Getachew2, Department of Pharmacology, Y. Tizabi2, Department of Pharmacology,  College of Medicine, Howard University, Washington, DC

THE DEPRESSIVE EFFECTS OF NICOTINE IN FEMALE WKY RATS

Cigarette smoking is considered to be the leading most preventable cause of disease and death in the United States. Smoking has been shown to cause heart disease, strokes, peptic ulcers and numerous cancers. Epidemiological reports have also shown that smoking and depression have a strong positive correlation.  However, a causal relationship for this co-morbidity between smoking and depression has not been established. It has been suggested that nicotine, the addictive agent found in all tobacco products, may, in some occasions act as anti-depressant and in other occasions to induce or exacerbate the depressive symptoms. Animal models and different behavioral paradigms have been used to investigate the association between nicotine use and depression. Most animal studies have consistently shown that nicotine has an anti-depressant-like effect. Depressive-like characteristics in rats are routinely evaluated by the measure of immobility in the forced swim test (FST), which is an established measure  to test the clinical efficacy of anti-depressants. In addition, to disassociate the effects of drugs on general locomotor activity (LCA) versus their specific effects on immobility in the FST, an open field activity is also included in behavioral evaluations. Recent studies in the lab have indicated that when nicotine is present in plasma, it may actually exacerbate the depressive-like characteristics of Wistar-Kyoto rats (WKY), a putative animal model of depression.  The present aim of the lab was to determine if pretreatment with the antidepressant desipramine would prevent the effects of nicotine. Adult female Wistar and WKY rats were administered nicotine acutely and twice daily for 8 days and their locomotor activity in the open field, as well as their immobility in the forced swim test were assessed 15 min after the last injection. It was found that 8 days of nicotine induced depressive-like characteristics in Wistar rats and exacerbated those of WKY rats, whereas acute nicotine did not have any effect on LCA or the immobility in the FST in either strain. Administration of a moderate dose of desipramine 10 min prior to nicotine injection did not blocked the effects of nicotine in the FST. Current studies are evaluating the effects of higher doses of desiparmine. It is hypothesized that pretreatment with an antidepressant would block the “depressogenic” effects of nicotine in the indicated paradigm.

Supported by:  NIH/NIGMS (2 SO6 GM08016-36) 

 

Biological and Life Sciences Division

 

ALEXANDRA E. SUTTON and KOBINA YANKSON, Department of Biology and Department of Fisheries and Aquatic Science, University of Cape Coast, Ghana, Graduate School, Howard University, Washington, DC

THE EFFECT OF SALINITY ON FILTRATION OF THE WEST AFRICAN MANGROVE OYSTER, Crassostrea tulipa

The potential for developing a fisheries industry based on the West African Mangrove Oyster is high in Ghana.  The oyster, Crassostrea tulipa, is a euryhaline organism that thrives in the coastal lagoons of the Ghanaian shoreline.  The organism is commonly known, yet further research should be done in preparation for a fishery development.  Subsequently, this experiment focused on exploring the precise relationship between salinity and filtration rates of the oyster.  Oysters gathered from two types of coastal lagoons (closed and open) were exposed to salinity varying from 0 ppt to 35 ppt and filtration rates were measured based on one-hour intervals.  Data showed that salinity had no significant effect on filtration rate of a given oyster type (p value = 0.91265, open lagoon; p value = 0.9965, closed lagoon).  However, significant difference did exist between the filtration rates of oysters collected from the two different types of lagoon (p value = 0.0002).  Oysters collected from the closed lagoon had a significantly greater mean filtration rate across all salinity levels than oysters collected from the open lagoon (0.3485ppm/min, open lagoon; 0.6567ppm/min, closed lagoon).  These differences in filtration rates may relate to adaptation for greater salinity variation in closed lagoons.

Supported by:  NSF Grant # 040515, Environmental Biology Scholars Program, Biology Department, Howard University, Dr. Mary A. McKenna, P.I., and by the NSF REU Program, Department of Biology, James Madison University, Harrisonburg, VA.

 

 

 

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